Senior scientist - antibody discovery

Job Description

Job Description

Role Overview

This is a unique opportunity to join an Antibody Discovery team working with cutting-edge technologies to help shape the delivery of next-generation antibody therapeutics.

This is an excellent opportunity to join a dynamic and thriving team of scientists helping to develop and validate new sequence-based and structure-based antibody design approaches. This includes elements of antibody hit identification, sequence optimization, and in silico de novo antibody design. This is a laboratory-based role where a detailed knowledge of molecular biology and microbiological methods, and a proven track record of antibody discovery or protein engineering would be a significant advantage.


Responsibilities

1. Play a key role in the discovery of therapeutic monoclonal antibodies to support the pipeline and help create value for patients suffering from serious diseases.
2. Use cutting-edge yeast display for the discovery and optimization of human antibodies aligned with therapeutic targets.
3. Design, construct, and perform selections using bespoke synthetic display libraries to support in silico de novo antibody discovery and optimization projects.
4. Prepare next-generation sequencing (NGS) libraries and analyze them to support antibody discovery and engineering of lead molecules.