Full‑time hours (37.5 h/week)
An exciting opportunity has arisen within the Research and Innovation Division at The Christie. We are looking to appoint a Senior Clinical Trials Coordinator to the Breast clinical research delivery team within The Christie NHS Foundation Trust.
We are seeking an enthusiastic and highly motivated individual, who is able to demonstrate significant work experience in clinical trials coordination and data management involving clinical trials or project co‑ordination, as well as a good understanding of clinical research, GCP and clinical governance.
Applicants should have excellent organisation and communication skills, can work well both in a team and using their own initiative. The individual must demonstrate good leadership skills that will promote an environment of quality and learning.
The role is ideal for individuals keen to pursue a managerial career in clinical trials coordination. It is tailored to equip the successful candidate with the necessary skills and experience to become a future leader in this field.
Applicants should meet all the essential criteria described in the job description as a minimum, including holding a scientific or business‑based degree, or have relevant experience in scientific and medical research.
Main duties of the job
The focus of this role is to provide support to sustain and improve an excellent level of service provision from a trial site perspective for our research partners. In order to support our growth as a centre of excellence in research, a tailored training programme will be provided to the successful candidate to consolidate the skills required to provide multi‑team management support for the Clinical Trial Research teams in the trust.
We are looking for an individual who will act as a key co‑ordinator for the Breast Research team to proactively ensure the provision of a high quality and efficient administrative service.
The role will include all phases of research and require the set up and coordination of complex clinical trials; previous experience of study set up of complex trials would be desirable. There will also be aspects of work allocation and support of coordination staff and direct line management responsibilities, along with oversight of team metrics. The post holder will be expected to provide managerial and leadership support to the senior R&I management and clinical research staff, and ensure compliance with Trust Policy, Good Clinical Practice (GCP) and all other relevant requirements.
Opportunities will be available to lead service development projects within the team and the wider R&I division.
Working for our organisation
The Christie is one of Europe’s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15 % of patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.
Detailed job description and main responsibilities
DUTIES AND RESPONSIBILITIES
TEAM SUPPORT
* Responsible for supporting and supervising workload allocation/ monitoring across administrative team members, escalating issues as appropriate to senior managers.
* Provide support to senior managers with general Human Resource activities, including but not limited to recruitment and selection and line management of administrative team members as required, in accordance with Trust policies.
* Provide induction support and training to new and existing clinical trials staff through one‑to‑one and group learning activities.
* Encourage the sharing of best practice and dissemination of information through regular structured meetings with all trials administration staff.
* Assist with data collection for divisional metrics reports of key performance indicators.
CLINICAL TRIALS CO‑ORDINATION/ DATA MANAGEMENT
* Act as a key point of contact with the core Research and Development team, study sponsors, clinical research organisations and specific research teams.
* Support feasibility activities for new studies under direction from senior managers and Principal Investigators.
* Manage the set up and initiation of allocated clinical trials within assigned Clinical Research Teams. Provide support for study set up and initiation that has been delegated to Clinical Trials Coordinators, escalating any delays as appropriate.
* Support with negotiations of study set‑up costs and income recovery for assigned clinical trials in conjunction with the Research Division’s Business Planning and Finance teams with oversight from senior managers.
* Oversee maintenance of investigator site files and essential documentation in accordance with ICH‑GCP and Trust Standard Operating Procedures (SOPs) to ensure they are kept inspection‑ready at all times.
* Oversee and process trial amendment submissions in accordance with ICH‑GCP and Trust SOPs and timelines, escalating any delays with the core Research and Development office as appropriate.
* Ensure, with the Clinical Research Team, that adverse event incidents and forms are completed, reported and followed up to resolution as the study protocol and regulations require.
* Implement and coordinate reporting mechanisms to ensure that research staff complete and return proformas containing up‑dated information on patients included in the study.
* Oversee and complete case report forms and participate in monitoring visits as per sponsor requirements.
* Liaise with internal staff and external collaborators to resolve queries.
* Provide information for senior managers including (but not limited to) case report form completion timeliness, data locks, data backlogs, work allocations and patient recruitment.
* Ensure that data is available and up to date for any meetings related to the trial/ study, producing minutes as required.
* Attend project‑related meetings, investigator meetings (abroad or teleconferences, as necessary) to convey the relevant information to the study team.
* Attend disease‑specific research team meetings to maintain an overview of team activity.
* Assist with preparation for audit and inspections within assigned teams and implementation of action plans.
* Ensure that all documents are archived in the appropriate way by following the Trust’s archiving guidelines.
* Undertake general administrative tasks as delegated by managerial representatives from the Research Division to contribute to the smooth running of the patient recruitment teams.
* Demonstrate the agreed set of values and be accountable for own attitude and behaviour.
WORKING PRACTICE
* Work closely with the Senior Research Management Team to implement new SOPs and working procedures within designated teams.
* Be pro‑active in providing feedback on working practices within the research team and suggest new ways of working.
* The post holder is expected to use initiative and be able to work independently without close supervision. They are also expected to plan and organise their own time and workload activity with prioritisation, referring to senior managers as necessary.
* The post holder is guided by relevant protocols and SOPs, and expected to exercise judgement outside these areas.
PERSONAL AND PEOPLE DEVELOPMENT
* Maintain professional development while evaluating own specialist knowledge with assistance from their assigned line manager to satisfy the NHS Knowledge and Skills Framework.
* Participate in and deliver Trust‑wide education programmes and study days, regional and national meetings and research seminars as appropriate.
PHYSICAL, MENTAL AND EMOTIONAL EFFORT
* Long periods of time spent using keyboard to input information and use of VDU for electronic communication.
* Prolonged concentration is regularly required (e.g. when checking through trial documentation and entering data into spreadsheets).
* Occasional exposure to distressed circumstances as trial patients are commonly suffering from terminal illnesses.
Person specification
Qualifications
* Degree in a science or health related discipline
* Relevant experience in scientific and medical research
* Post graduate certificate in clinical research or other relevant post graduate qualification
* In possession of or working towards an NHS leadership academy qualification
Experience
* Significant experience in clinical trial administration and clinical trial data management
* Experience of mentoring junior staff
* Previous experience of working in the NHS or other healthcare system
* Involvement in education and staff development
Skills
* Ability to prioritise own and others workload and practice effective time management
* IT literate including good understanding and demonstrated use of the full Microsoft Office suite
* Accuracy and attention to detail
* Excellent interpersonal skills
* Advanced use of spreadsheets
Knowledge
* Good understanding of the clinical research delivery processes, related standards, governance and legislation
* Understanding of medical terminology and cancer
* Understanding of case report forms
* Knowledge of patient information systems
Values
* Ability to demonstrate the organisational values and behaviours
Other
* Ability to work to tight and/or unexpected deadlines
* Flexible with ability to adapt to service requirements
* Conscientious and hardworking
* Ability to work unsupervised or as part of a team
* Tactful and diplomatic
* Evidence of achievement under pressure
The Christie NHS Foundation Trust is committed to creating a balanced and diverse workforce. We welcome and encourage applications from people of all backgrounds, including from Black, Asian and other ethnic minority people and people with disabilities.
As users of the disability confident scheme, we guarantee to interview all disabled applicants who meet the minimum criteria for the vacancy.
The Christie NHS Foundation Trust is committed to the highest standards of ethical conduct and integrity in all our activities. We have a zero‑tolerance approach to modern slavery in any of its forms, including slavery, servitude, forced or compulsory labour, and human trafficking. We are fully committed to acting ethically and with transparency in all our business dealings and relationships, and to implementing and enforcing effective systems and controls to ensure modern slavery is not taking place anywhere in our organisation or supply chains.
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