Principal Biostatistician Global CRO | Dedicated FSP Partnership | Permanent | Remote - UK & Across Europe
A leading global CRO is looking to appoint an experienced Principal Biostatistician to join a dedicated Functional Service Provider (FSP) team supporting a portfolio of real-world evidence (RWE), pharmacoepidemiology, outcomes research, and non-interventional studies.
This role offers the opportunity to work on high-profile projects that generate evidence to inform healthcare decision-making, leveraging a range of real-world data sources including electronic health records (EHR), claims databases, patient registries, and other observational datasets.
As a senior member of the team, you will provide statistical leadership across a diverse portfolio of studies, collaborating closely with clients, scientific experts, and multidisciplinary teams to deliver robust and impactful research.
Key Responsibilities
* Lead the statistical design, analysis, and interpretation of real-world evidence, pharmacoepidemiology, and non-interventional research studies.
* Develop, review, and contribute to study protocols, Statistical Analysis Plans (SAPs), and study reports.
* Design and execute analyses using a variety of real-world data sources, including EHRs, healthcare claims databases, and registries.
* Apply advanced pharmacoepidemiological methodologies to support safety evaluations and comparative effectiveness research.
* Act as a statistical subject matter expert, providing scientific guidance to clients and internal stakeholders.
* Partner with cross-functional teams to ensure high-quality study delivery and scientific excellence.
Candidate Profile
To be successful in this role, you will bring a strong background in biostatistics and observational research, together with a passion for generating meaningful evidence from real-world data.
Essential Requirements
* MSc or PhD in Biostatistics, Statistics, or a related quantitative discipline.
* Minimum 9 years of biostatistics experience with an MSc, or 7 years with a PhD.
* Extensive experience within real-world evidence, pharmacoepidemiology, and non-interventional research.
* Proven expertise working with observational healthcare data, including EHRs, claims databases, and patient registries.
* Strong programming capability in R (essential).
* Experience authoring and reviewing study protocols and Statistical Analysis Plans.
* Comprehensive understanding of the biases and limitations associated with claims data, particularly US healthcare claims, and EHR-based analyses.
* Practical experience with observational study designs including cohort studies, self-controlled study designs, and target trial emulation.
* Knowledge of advanced analytical methodologies such as propensity score techniques, clone-censor-weighting approaches, and time-to-event analyses.
Desirable Experience
* Previous experience within vaccines and/or infectious disease research would be highly advantageous.
What's on Offer?
* Competitive salary and comprehensive benefits package including medical, dental and vision coverage, pension scheme, life insurance, and fitness subsidy.
* Fully home-based position with flexibility to work from a range of European locations, including the UK, Spain, Belgium, France, Germany, Italy, Poland, and the Netherlands.
* Opportunity to work within a long-term, dedicated FSP partnership supporting a leading global client.
* Exposure to cutting-edge real-world evidence, pharmacoepidemiology, and outcomes research programmes.
* Excellent opportunities for professional growth, development, and long-term career progression.
Interested?
If you're an experienced Principal Biostatistician looking to take the next step in your career, we'd be delighted to hear from you. Apply today with your CV to be considered for this opportunity.
Exploring Other Opportunities?
For a confidential discussion about this role or other Biostatistics opportunities across the UK and Europe, please contact Aimee Weston at aimee@warmanobrien.com.