Overview
* United States - Massachusetts - Cambridge
* United States - Connecticut - Groton
* United States - New York - New York City
We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.
To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.
Primary Duties
* Provides pharmacometric expertise and leadership to projects.
* Responsible for developing model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision-making, in collaboration with partners.
* Responsible and accountable for conducting and reporting quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development.
* Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety.
* Acts as pharmacometric Subject Matter Expert (SME), including proactive support and development of quantitative methodology, software, automation, hardware, tools, and related business processes, in addition to training to the global clinical pharmacology organization.
* Responsible for the pharmacometric leadership and support in preparation and defense of regulatory submissions.
Training, Education and Experience
* At least 5 years of experience in pharmacostatistical modeling and application of MIDD.
* An interest and experience of pharmacostatistical methods of data analysis and study design are essential.
* Ideal qualifications include Pharm.D, PhD, or equivalent training, or equivalent expertise in one or more areas related to pharmacostatistical modeling (e.g., pharmacometrics, pharmacokinetics, clinical pharmacology, statistics, or related discipline).
* Candidates from alternative backgrounds (e.g., mathematics, engineering, system biology, medicine) will be considered if they can demonstrate relevant experience and expertise.
* Strong science and quantitative analysis background, with good working knowledge of pharmacokinetics, pharmacology, pharmaceutics, and/or statistics.
* Basic understanding/knowledge of biology, physiology/pathophysiology, and drug research & development process.
* Good computational skills.
* Good knowledge of a range of MIDD software (R, NONMEM, STAN, etc.).
Competency
* Pharmacometrics: demonstrates thorough understanding, and application, of quantitative modeling and simulation principles.
* Communication Skills: demonstrates excellent verbal and written communication skills.
Organizational Relationships:
* Reports to Pharmacometrics Group Leader or Head of Pharmacometrics and Systems Pharmacology within the line organization of Pharmacometrics and Systems Pharmacology, Translational Clinical Sciences.
* Matrixed relationships particularly with Clinical Pharmacology Leads, QSP modelers, Clinicians, Statisticians, and colleagues from Pharmacokinetics, Dynamics and Metabolism (PDM), and other groups as required.
Work Location Assignment:Hybrid
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Position Purpose
* Provides pharmacometric expertise and leadership to projects.
* Responsible for developing model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision-making, in collaboration with partners.
* Responsible and accountable for conducting and reporting quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development.
* Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety.
* Acts as pharmacometric Subject Matter Expert (SME), including proactive support and development of quantitative methodology, software, automation, hardware, tools, and related business processes, in addition to training to the global clinical pharmacology organization.
* Responsible for the pharmacometric leadership and support in preparation and defense of regulatory submissions.
Benefits and Compensation
The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
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