Job Description
Grade UE06: £34,610 to £39,906 per annum, pro-rata if part time
CMVM / Centre for Clinical Brain Sciences
Part-time: 21 hours per week
Fixed term: 24 months
We seek an energetic, organised, motivated Assistant Trial Manager for the LACunar Intervention Trial 3 (LACI-3) that aims to improve outcomes after small vessel stroke funded by the National Institutes of Health and Care Research (NIHR).
The Opportunity
LACI-3 is the largest and only Phase 3 trial in small vessel (lacunar) stroke in the world, a major cause of stroke and vascular dementia, currently with no effective treatment.
As the Trial Research Data Administrator for LACI-3, you will be responsible for monitoring data accuracy and completeness in real time, liaising with sites and other LACI-3 team members amongst other factors. Your role will be crucial to ensure high-quality, complete and successful data collection for this high-profile trial.
You will work closely with the LACI-3 Trial Manager and central teams at the Universities of Edinburgh and Nottingham, and Site teams. You will assist the Trial Manager and Team with other activities, as appropriate to the stage of LACI-3, including managing the trial email inbox, providing trial materials to sites, and assisting Follow-up Co-ordinators.
This post is full or part-time (minimum 21 hours per week); however, we may consider flexible working patterns. The post is primarily office based, but we may consider requests for a mix of office and home (hybrid) working (on a non-contractual basis).
The salary for this post is UE06
Your Skills And Attributes For Success
* You will have experience in clinical trials data management and research administration;
* You will have excellent organisational and data accuracy skills;
* You will have experience of multicentre trials including liaison with site staff and primary care;
* You will have up to date knowledge of research ethics and R&D principles, and of Good Clinical Practice with an up-to-date GCP certificate.
Click to view a copy of the full job description (opens new browser tab)
Please ensure you include the following documents in your application:
* CV stating qualifications, employment experience, other relevant research experience, current UK visa status and right to work;
* Cover letter stating your reasons for applying for the post, your interest and experience of stroke trials
As a valued member of our team you can expect:
* A competitive salary
* An exciting, positive, creative, challenging and rewarding place to work.
* To be part of a diverse and vibrant clinical trial community
* Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our staff benefits page (opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits
Championing equality, diversity and inclusion
The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.
Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our right to work webpages (opens new browser tab)
On this occasion the University will not consider applicants requiring sponsorship for this role. International workers will therefore only be able to take up this role if they can demonstrate an alternative right to work in the UK.
Key dates to note
The closing date for applications is the 15th of December 2025
Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.
Interview dates TBC
About Us
As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.
About The Team
Centre for Clinical Brain Sciences
The Centre for Clinical Brain Sciences (CCBS; Director Professor Colin Smith), part of Edinburgh Medical School and Edinburgh Neuroscience, integrates laboratory and clinical research to study the causes, consequences and treatment of major brain disorders. Anchored in the Edinburgh BioQuarter adjacent to the Royal Infirmary of Edinburgh, and with bases at other Edinburgh hospital sites, CCBS’ locations link clinical and laboratory science with informatics and commerce to encourage the free-flowing exchange of ideas, the efficient use of clinical data and joint academic/health service delivery.
CCBS comprises 64 Principal Investigators (47 staff and 17 honorary)—including 21 Personal Chairs. Of these, 70% are active NHS clinicians, which grounds the Centre’s research aims close to unmet clinical need and facilitates the translation of research findings into real-world impact. The 300+ members of CCBS conduct research of international recognition and reputation and publish approximately 300 papers a year. Major strengths include clinical trials and trial methodology, neuroimaging, neuropathology and regenerative neurology (including human stem cell research) in a wide range of conditions encompassing brain vascular disease/stroke, neurodegenerative disease, prion disease and psychiatric disorders. CCBS researchers attracted £57M in grant-funding over the last three years and collaborate widely, leading national and international clinical trials in stroke (e.g. IST-3, FOCUS, RESTART) and dementia (e.g. EPAD, AMYPAD) and playing a major role in the UK Dementia Research Institute at the University of Edinburgh. The National CJD Research and Surveillance Unit is a WHO Reference Centre for Human Prion Disease. The research generates significant and measurable impact in terms of patient health and wellbeing, NHS policy and economy, and public awareness.
Within Edinburgh University’s REF 2021 submission the second largest submission was for “Neuro”; that is formally classified as Psychology, Psychiatry and Neuroscience (Unit of Assessment 4). Edinburgh was ranked second in the UK by quality (‘grade point average’, according to Research Professional) and third in the UK by the ‘power’ measure which takes into account the size of the submission as well as the quality (according to Times Higher Education; up from 4 th in the last REF in 2014). The combined metric of quality and power places Edinburgh 1st in the UK. 52% of our research papers were awarded the highest score of 4*, defined as world-leading, and a further 38% were rated 3*, defined as internationally excellent. 100% of our ten impact case studies – measuring health and wealth gain- were awarded 4*, meaning they are world-leading in reach and significance. Importantly 100% of our environment was awarded 4*, meaning the context in which our research takes place is world-leading in vitality and sustainability.
CCBS currently has 49 postgraduate students, mostly PhDs. It is particularly strong in clinical PhD training, with a number of innovative schemes including Rowling Scholars and Princess Margaret Research Development Fellowships. The Edinburgh Imaging Academy is a flagship for e-learning MSc and CPD courses. The Centre also has a strong record of attracting philanthropic donations to establish specialist research hubs (Anne Rowling Regenerative Neurology Clinic, Euan MacDonald Centre for MND Research, Edinburgh Dementia Prevention, MS Society Edinburgh Centre for MS Research, Muir Maxwell Epilepsy Centre, Salvesen Mindroom Research Centre, Sackler Institute for Psychobiological Research, Row Fogo Centre) that are maintained and expanded by community fundraising.
For further information about our Centre is available on the Centre for Clinical Brain Sciences Website ( https://www.ed.ac.uk/clinical-brain-sciences ) (opens in a new browser tab).