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Senior clinical data manager

London
Clinical data manager
Posted: 21h ago
Offer description

We have a great role for a Senior Clinical Data Manager working for a client. As a Senior Clinical Data Manager, you will lead the end-to-end Data Management lifecycle for complex or pivotal clinical trials. You'll own data quality, standards, compliance, and delivery-from database design through to database lock and submission-acting as the senior point of accountability across programs. You will drive best practice, guide cross-functional alignment, and ensure that high-quality, regulatory-ready data underpins critical clinical and regulatory decisions. Key Responsibilities Startup & Planning Lead database design, CRF development, edit checks and data flow planning Develop Data Management Plans, validation specs and standards Ensure consistent application of CDISC and controlled terminology Execution & Quality Oversight Oversee data review, queries, coding, reconciliation and quality checks Act as the primary DM contact for Clinical, Biometrics and vendors Identify risks early and implement process improvements Support interim analyses, safety reviews and IDMC/DSMB data needs Closeout & Submission Lead database lock, ensuring all data are complete, reconciled and audit-ready Deliver clean, submission-ready datasets and documentation Ensure full compliance with GCP/ICH and 21 CFR Part 11 What You Bring Strong experience running studies in Clinical Data Management on complex/global studies Expert knowledge of EDC systems, CDISC standards and coding dictionaries Strong understanding of ICH-GCP, 21 CFR Part 11 and regulatory requirements Experience mentoring or guiding team members Proven ability to manage vendors, timelines and quality in fast-paced environments Who You Are Strategic thinker with strong attention to detail Skilled communicator and natural cross-functional collaborator Contact David Atkin for more information datamanager clinicaldata

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