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Research Assistant in Organoid/iPSCs models, Oxford Client: University of Oxford
Location: Oxford, United Kingdom
Job Category: Other
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EU work permit required: Yes
Job Reference: e9fe01a9fe22
Job Views: 8
Posted: 22.06.2025
Expiry Date: 06.08.2025
Job Description: We are seeking a highly motivated Research Assistant to join Dr Giulia Orlando's research group in the Department of Oncology at the University of Oxford. This role supports research on RAS pathway activation in gene regulation and tumour development in colorectal cancer. The project employs advanced technologies such as bulk RNAseq, ATACseq, and 10X single-cell multiome, combined with 3D organoid models, iPSCs, and primary patient samples to identify new therapeutic targets. Responsibilities include developing APC/KRAS mutant models via CRISPR and creating co-culture systems to study epigenetic changes in the tumour microenvironment. You will receive training in organoid culturing, CRISPR editing, FACS, and genomics techniques, with opportunities for collaboration and scientific growth. This is a full-time, fixed-term position for 1 year.
About you : You will hold an undergraduate degree in genetics, biochemistry, molecular biology, or a related field, with a keen interest in epigenetics, cancer biology, and tumour microenvironment. Strong organizational skills, independence, and teamwork abilities are essential.
What We Offer : We prioritize employee wellbeing and offer benefits including:
An excellent contributory pension scheme
38 days annual leave including bank holidays (pro-rata for part-time)
Comprehensive childcare services
Family leave schemes
Cycle loan scheme
Discounted bus travel and Season Ticket loans
Membership to social and sports clubs
Application Process : Applications must be submitted online.
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