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Senior biostatistician

Metric Bio
Biostatistician
€125,000 - €150,000 a year
Posted: 16 June
Offer description

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Placing the top 1% of commercial talent in the market. Navigating the CDMO/CRO market & leading The European commercial team at Metric Bio

Our partner

A leading full-service contract research organization (CRO) is seeking a Senior Biostatisticianto join its team. With a global presence and a strong foundation in statistical and data management, the company supports a range of clients in pharmaceutical, biotechnology, and medical device with their clinical development programs.

Your responsibilities

* Provide statistical expertise for the design, analysis, and reporting of clinical trials and research projects.
* Contribute to writing statistical sections of protocols, conduct sample size calculations, develop randomization specifications, and generate codes.
* Write Statistical Analysis Plans (SAPs) and address peer statistician feedback.
* Create and maintain Statistical and Programming Quality Control (QC) and Quality Assurance (QA) Plans.
* Provide input on unblinded data management plans where necessary.
* Support the development and refinement of statistical methodologies and internal processes.
* Perform statistical analyses according to the SAP and respond to QC review comments.
* Conduct statistical validation of key results and address additional review feedback.
* Contribute to trial result dissemination meetings and documentation.
* Assist with the statistical components of Clinical Study Reports (CSRs), including writing and reviewing for accuracy and interpretation.
* Conduct statistical analyses for abstracts, manuscripts, presentations, and posters.
* Develop and/or review ADaM dataset specifications; review SDTM specifications as needed.
* Perform QC validation of datasets and tables/listings/figures (TLGs).
* Conduct third-level reviews of dry and final runs.
* Lead statistical dry and final runs, manage resources, and collaborate with programming and data management teams.
* Provide input and respond to feedback for the Analysis Data Reviewer’s Guide.
* Offer statistical input on Case Report Forms (CRFs) and variable/database structure.
* Provide guidance for non-CRF data collection methods.
* Review Data Management Plans, focusing on critical data collection and cleaning.
* Define or program database quality checks, assess/report data issues, and track to resolution.
* Monitor data quality, including protocol deviations, and support data lock preparation.
* Lead resolution of operational challenges, ensuring quality and efficiency.
* Manage assigned projects using project management and statistical expertise to deliver high-quality results on time and foster client satisfaction.
* Follow internal policies, standard operating procedures (SOPs), and sponsor work instructions.
* Archive study documentation in line with sponsor requirements.

Requirements

* A Ph.D. degree in statistical science, mathematical analysis or related fields
* 3+ years relevant biostatistical experience
* Proven ability within a clinical trial environment.


Seniority level

* Seniority level

Mid-Senior level


Employment type

* Employment type

Full-time


Job function

* Job function

Research, Science, and Information Technology
* Industries

Research Services, Biotechnology Research, and Pharmaceutical Manufacturing

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