Opportunity status:
Open
Funders:
Funding type:
Grant
Publication date:
7 April 2026
Opening date:
7 April 2026 9:00am UK time
Closing date:
Open - no closing date
Apply for funding to take the next step towards becoming an independent researcher.
Doing exciting and ambitious research in the remit of the Medical Research Council (MRC). To drive important insights into causes and mechanisms of disease and help accelerate diagnosis, advance treatment and prevent human illness.
You must have:
* the skills and experience to ‘transition to independence’
* the support of an eligible host research organisation
There is no limit to the funding you can apply for.
MRC will fund 80% of the full economic cost (FEC) and 100% of exceptions.
Funding is available for up to five years, for up to 50% of your salary.
This funding opportunity is open to organisations with standard eligibility. .
Who is eligible to apply
To be eligible to apply as a new investigator you must:
* have
* be able to show that your skills and experience match those in the ‘transition to independence’ stage of the
* use this grant to support your long-term career goals and chosen career route
* be able to demonstrate you are the sole intellectual leader of the application and the proposed work
If you meet the eligibility criteria, you can also apply if you:
* are employed as a postdoctoral research assistant, although this grant cannot start until your current work finishes
* hold a lecturer appointment, a junior fellowship or another research staff position
* hold, or have held, an early career training fellowship such as an MRC skills development fellowship
* are not currently based at the eligible research organisation that has agreed to host your new investigator award
* are either a non-clinical or clinically active researcher
* have any number of years of experience
For applicants who do not have a contract of employment for the duration of the proposed project, by submitting an application the research organisation is confirming, if it is successful:
* contracts will be extended beyond the end date of the project
* all necessary support for the project and the applicants will be provided, including mentorship and career development for early career researchers
Demand management
You can only be project lead on one application at a time across MRC’s applicant-led responsive funding opportunities (research, partnership and new investigator). If you submit another application while one is being assessed, the new application will be rejected. You should wait until you receive a decision on your current application before submitting another.
Resubmissions
You may apply twice for an MRC new investigator award. If you are applying for a second time we invite you to resubmit your first application, or your second application may be a new application.
We advise you to allow sufficient time between applications to consider and respond to feedback.
Who is not eligible to apply
You are not eligible to apply if you have already achieved independence. New investigator awards support individuals who have not previously led a research team or been awarded a substantial grant as fellow or project lead (formally known as principal investigator).
A substantial grant is typically defined as for three or more years and including salary support for one or more additional team members.
You are also not eligible to apply if you:
* already hold or have held an award that facilitates the transition to independence
* have applied for an MRC new investigator award twice before
* have an application for any UK Research and Innovation (UKRI) fellowship currently under consideration, including a, or
If you are unsure whether you meet the eligibility criteria or have any questions about your eligibility you should contact us to find out whether you can apply. Find contacts in the ‘contact details’ section.
You are not eligible to apply for this funding opportunity as a project lead if you are based at an international research organisation. This does not include project leads from MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine (LSHTM) or MRC/UVRI (Uganda Virus Research Institute) and LSHTM Uganda Research Unit.
If you are employed by these organisations you cannot apply as project lead or project co-lead, but can participate as project partners on an application led by an eligible UK organisation:
* businesses
* charity and third sector organisations
Charities and third sector organisations that are approved UKRI Independent Research Organisations are eligible to apply as project lead or project co-lead.
Project co-leads and other team members
We recognise and support the value of team science and interdisciplinary research, which may be important to your career development. Therefore, project co-leads, specialists and other team roles may be included within your new investigator application. Your team members should bring essential complimentary research, technical expertise or skills to the project, that you as the new investigator project lead cannot provide, or you are aiming to develop.
We encourage you to use the appropriate application sections, such as ‘Applicant and team capability to deliver’, to make your leadership role clear and justify the team around you.
It is not usually appropriate for a current or recent supervisor or lab head of the new investigator to be part of the applicant team, as this may make your leadership unclear. If this is essential to the proposed work, it must be specifically justified.
International researchers
As MRC is a lead funder for this funding opportunity, international researchers, can apply as project co-lead (international).
Project co-leads (international) make a major intellectual contribution to the design or conduct of the project. Their contribution and added value to the research should be clearly explained and justified in the application, see Applicant and team capability to deliver.
Read the for more details.