Molecular and Cell Biology Senior Research Scientist
Join to apply for the Molecular and Cell Biology Senior Research Scientist role at Vertex Pharmaceuticals
Molecular and Cell Biology Senior Research Scientist
Join to apply for the Molecular and Cell Biology Senior Research Scientist role at Vertex Pharmaceuticals
General Summary:
Our Human Disease Modelling group is seeking an innovative and dynamic Senior Research Scientist to play a pivotal role in expanding our capabilities in disease-relevant human cell models at the Oxford Research site. Successful candidates would help us utilise a range of technologies to build such models that can be leveraged to test therapeutic hypotheses, discover novel target biology, characterise potential drug candidates and develop translational biomarkers. This position will involve working in close collaboration with other researchers and across drug discovery disciplines to ensure that we deliver medicines that treat the underlying cause of serious diseases and provide transformative benefits for our patients.
Job Description
General Summary:
Our Human Disease Modelling group is seeking an innovative and dynamic Senior Research Scientist to play a pivotal role in expanding our capabilities in disease-relevant human cell models at the Oxford Research site. Successful candidates would help us utilise a range of technologies to build such models that can be leveraged to test therapeutic hypotheses, discover novel target biology, characterise potential drug candidates and develop translational biomarkers. This position will involve working in close collaboration with other researchers and across drug discovery disciplines to ensure that we deliver medicines that treat the underlying cause of serious diseases and provide transformative benefits for our patients.
Key Responsibilities
* Independently design and (where appropriate) execute and elaborate technically challenging experiments using disease-relevant cell-based models to test therapeutic hypotheses
* Champion and leverage cutting-edge molecular cell biology techniques and technologies for in vitro disease modelling
* Effectively distil complex, multi-dimensional data and results into concise concepts and propose strategic and experimental actions
* Proactively communicate and work highly effectively within and between teams
* Collaborate extensively and work on shared projects with other scientific colleagues and cross-functional teams, including others in the Biology Dept and beyond
Key Requirements
* PhD in a relevant Biological Science (e.g. Molecular or Cellular Biology) or equivalent years of experience in an industry setting
* Strong cell biology background, with experience culturing hiPSCs and/or a broad range of cell systems, such as human primary cell systems or organoids
* Experience in multi-parametric flow cytometry and other assay formats, such as high-throughput imaging, single-cell technologies, to characterise disease mechanisms at the cellular level
* Versatile molecular biology experience, including qPCR, cloning, Western Blot, aLISA, IHC and other cellular assays
* Proven track record for solving complex scientific problems and delivering high-quality results, as demonstrated through an excellent publication history, supported by evidence of major individual contributions
* Very strong verbal and written communication and teamwork skills
* Motivated and curious; excellent team player, happy to work across a broad range of biological subjects and projects to identify the molecular drivers of disease.
* LI-SG-1
Flex Designation
On-Site Designated
Flex Eligibility Status
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
Seniority level
* Seniority level
Mid-Senior level
Employment type
* Employment type
Full-time
Job function
* Job function
Other
Referrals increase your chances of interviewing at Vertex Pharmaceuticals by 2x
Get notified about new Senior Research Scientist jobs in Oxford, England, United Kingdom.
Principal Scientist I Analytical Development
Oxford, England, United Kingdom 1 week ago
Principal Scientist I Analytical Development & Validation
Oxford, England, United Kingdom 1 week ago
Oxford, England, United Kingdom 4 months ago
Principal Scientist I Analytical Development & Validation - Oxford
Oxford, England, United Kingdom 1 week ago
Associate Principal Scientist Material Sciences
Reading, England, United Kingdom 4 days ago
High Wycombe, England, United Kingdom 1 week ago
Oxford, England, United Kingdom 2 weeks ago
Oxford, England, United Kingdom 4 months ago
Scientist/Senior Scientist, Characterization of Biologics...
Oxford, England, United Kingdom 3 weeks ago
Senior Scientist Applications - Pathogen
Oxford, England, United Kingdom 2 weeks ago
Oxford, England, United Kingdom 2 weeks ago
Oxford, England, United Kingdom 1 month ago
Lead / Principal Scientist Chemical Engineering, Aluminium Hydroxide
Aylesbury, England, United Kingdom 5 days ago
Senior Scientist (Next-generation sequencing) - Generative Biology Institute
Oxford, England, United Kingdom 1 month ago
Senior Scientist I - Characterisation | CMC - Oxford
Oxford, England, United Kingdom 6 days ago
Principal Scientist/Deputy Director of Education
Lead / Principal Scientist – Chemical Engineering, Aluminium Hydroxide, Green Hydrogen, Material Science, Mainly Onsite (Aylesbury) c.£85k + Benefits (Negotiable)
Oxford, England, United Kingdom 2 weeks ago
Principal Scientist – Biocompatibility & Product Development
Witney, England, United Kingdom 3 weeks ago
Senior Scientist in Electron Ptychography (10369)
Harwell, England, United Kingdom 5 days ago
Senior Laser Scientist Fusion Laser Driver Development UPLiFT
Didcot, England, United Kingdom 1 month ago
Senior Laser Scientist Fusion Laser Driver Development UPLiFT
Didcot, England, United Kingdom 2 weeks ago
We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr