For 75years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well:being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
Job Summary
The Chromatographic Bioanalysis department is a large team located at our site in Tranent, East Lothian. We are looking for a Research Scientist to join the method development team within the department, to participate in the development of quantitative assays on our fleet of over 20 high spec LC MS instruments.
As a CRO we have the opportunity to work with a large variety of analytes, from small polar molecules to peptides, proteins, nanoparticles and oligonucleotides. This broad range of analytes and our involvement in a large variety of programme designs, from early:stage pre:clinical investigative work to in:vitro biosimilar evaluation and clinical trials, means that we are always expanding our knowledge and skills. As well as our ever:evolving workflow, our consistent involvement with the industry through conferences, literature, and multi:company project teams, provide additional opportunities for development of both the industry and individuals.
In this role you will act as a scientific expert, as well as planning and organizing for the efficient development of bioanalytical methods. This will involve using a variety of analytical techniques, or undertaking original research to develop new techniques, to establish methods suitable for generating data in a regulatory environment in a timely and cost:effective manner.
In more detail the role will include:
:Responsibility for the development of LC conditions, optimizing MS/MS parameters and refining extraction procedures for the quantitative analysis of analytes from biological matrices. Including responsibility for decision making based on the data generated.
:Routinely communicating effectively with internal and external stakeholders regarding study organization, progress, and challenges.
:Leading complex troubleshooting, both during method development studies and in collaboration with other teams during later stages of an assays usage
:Contribution to the generation of scientific papers and presentations
:Proactively mentoring junior method development scientists, to promote talent development.
:Demonstrating innovation through development of alternative scientific approaches and improvement of existing processes.
Job Qualifications
Applicants should have:
:A minimum of a BSc or equivalent in a scientific analytical related discipline.
:Familiarity with the use of standard laboratory equipment and analytical instrumentation.
:Experience developing assays in an analytical laboratory, preferably in a bioanalytical department.
:An understanding of appropriate regulatory guidance in bioanalytical method validation in addition to current GLP/GCP regulations
:Excellent communication (verbal and written), presentation and interpersonal skills.
:Effective decision:making skills and the ability to work independently in a fast:paced environment.
:A proven level of problem:solving ability and adaptability, in relation to both scientific and project management challenges.
:Experience supervising and developing junior colleagues.
:A proven ability to identify, design and conduct research projects based on analysis of industry trends.
Additionally, familiarity with protein analysis and HRMS workflows would be highly beneficial for the role.
Closing date for applications is Monday 1st September COB
The annual salary for this role is : GBP 40, 470.57
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