PDRA Computing for Integrated Structural Biology
Join to apply for the PDRA Computing for Integrated Structural Biology role at University of Southampton
PDRA Computing for Integrated Structural Biology
2 days ago Be among the first 25 applicants
Join to apply for the PDRA Computing for Integrated Structural Biology role at University of Southampton
Summary: We offer a post in scientific computing in structural biology. To bring together electron microscopic and crystallographic structural information, you will and develop routines to combined heterogeneous data types in an existing molecular visualization software. You will develop a practical and immediately useful application that enables integrative modelling of a macromolecular structure from multiple techniques. This will allow researchers to visualise and ‘manually weight’ different types of information from different sources globally and locally across a macromolecular structure, and pipe into structure refinement and validation. The framework for this work is already set up, as you will join a team of programmers.
The project: Specifically, you will work on the coot / moorhen project. In the phase funded initially the project will focus on reading in electron and nuclear density maps from macromolecular crystallography and electron microscopy. The aim is to create routines that are extensible and will allow adaptation to further data formats in future. This will be done in a second phase (extension) and may include small angle X-ray scattering (SAXS), NMR, molecular modelling, or biophysical experiments (e.g. native/Hdx-MS, SPR or FRET).
Qualifications: Proficiency in at least one computer language as in C++ and/or Python is required. This project also uses Javascript, REACT, and GTK. Experience in structural biology in at least one technique is also required.
The Post: This post is part of the DRI-IMB network, an initiative of UKs Digital Research Infrastructure with the vision to integrate computing across the biosciences and funded through CoSeC. It is shared between the collaborative computing projects for macromolecular crystallography and electron microscopy, CCP4 and CCPEM. Primary location of the post is the Research Complex at Harwell, while you will also work with the Moorhen and Coot teams at York and the LMB Cambridge. Initial appointment is for one year but can be extended to three years.
Contact: For more information on the post please contact Ivo Tews – University of Southampton, e mail: ivo.tews@soton.ac.uk and Tom Burnley - STFC UKRI, e mail: tom.burnley@stfc.ac.uk.
Application: Apply by uploading your CV and a cover letter detailing how your skills and experience match the requirements of the role.
Seniority level
* Seniority level
Entry level
Employment type
* Employment type
Full-time
Job function
* Job function
Research, Analyst, and Information Technology
* Industries
Higher Education
Referrals increase your chances of interviewing at University of Southampton by 2x
Sign in to set job alerts for “Biology Specialist” roles.
Southampton, England, United Kingdom 2 weeks ago
Southampton, England, United Kingdom 2 weeks ago
Southampton, England, United Kingdom 2 weeks ago
Southampton, England, United Kingdom 2 weeks ago
Southampton, England, United Kingdom 3 weeks ago
Portsmouth, England, United Kingdom 1 month ago
Southampton, England, United Kingdom 1 month ago
Southampton, England, United Kingdom 2 weeks ago
Southampton, England, United Kingdom 2 weeks ago
Research Associate - Inorganic Chemistry
Stoke, England, United Kingdom 2 weeks ago
PDRA Computing for Integrated Structural Biology
Southampton, England, United Kingdom 4 days ago
Portsmouth, England, United Kingdom 3 weeks ago
We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr