Join to apply for the Principal Statistical Programmer role at Cancer Research UK (CRUK).
Location: Stratford, London – Office-based with high flexibility (1–2 days per month in the office).
Contract: Permanent; Hours: Full time, 35 hours per week.
Reports to: Lead Statistician; Directorate: Research & Innovation.
Closing date: 16 November 2025 23:55.
Responsibilities
* Lead the Statistical Programming strategy, providing technical leadership and oversight across the CDD portfolio.
* Develop SOPs, guidance documents, standards, and processes related to Statistical Programming, ensuring alignment with Clinical Data Interchange Standards Consortium (CDISC) standards and regulatory expectation.
* In collaboration with the Lead Statistician and key stakeholders, determine an optimised and innovative reporting process for CDD trials and manage related budgets.
* Liaise and work with other CDD Managers to maintain oversight of project status, risks and quality against project goals and key metrics. Escalate issues where appropriate.
* Oversee vendor partnerships and ensure consistent quality and compliance of outsourced statistical programming activities.
* Where appropriate, fulfil the role of a statistical programmer for CDD-sponsored clinical studies, providing hands‑on statistical programming support.
* Provide oversight, review and QC statistical deliverables from vendors (e.g. Dataset specifications, Statistical Analysis Plans, Tables, Listings, Figures, etc.).
* Ensure adherence to global regulatory requirements, internal SOPs, and industry best practices.
Qualifications
* Degree or equivalent experience in mathematics, statistics, computer science, life sciences or related field (preferable PhD or Masters).
* Extensive experience working as a statistical programmer on oncology clinical trials.
* Extensive Expertise in SAS programming.
* Significant understanding of drug development, including complex endpoints.
* Early phase development experience would be beneficial.
* Proactive and self‑motivated to drive change and improvements.
* Collaborative and influential with good relationship building skills.
Benefits
We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high‑quality tools. Our policies and processes enable you to improve your work‑life balance, take positive steps in your career and achieve your personal wellbeing goals.
Application Process
Please complete the work history section of the online application form. CVs are required for all applications; we will invite you for an interview if your profile matches the role. For more information or if you need adjustments to the application process, contact recruitment@cancer.org.uk or 020 3469 8400.
Equal Opportunity Employer
Cancer Research UK is an equal opportunity employer. We actively encourage applications from people of all backgrounds and cultures, in particular those from ethnic minority backgrounds who are currently under‑represented.
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