Overview
Join us at the world-leading CRUK Cambridge Institute. We're a unique department of the University of Cambridge, core funded by Cancer Research UK's charitable activities, and we're eagerly searching for our new post-doctoral Research Associate to join the Biffi Group.
We're seeking an experienced and motivated scientist, with a background in cancer research, and strong skills in cell biology and mouse work to join a team working on studying and targeting metastasis and the tumour microenvironment of pancreatic cancer.
The team combines ex vivo murine pancreatic tumour organoid/fibroblast co-cultures with murine in vivo models and patient samples to study and target the interactions between pancreatic cancer cells and the surrounding microenvironment.
For up-to-date information about the group, please see our websites: https://www.cruk.cam.ac.uk/research-groups/biffi-group https://biffilab.wordpress.com/our-team/
Responsibilities
* Lead a developing project in the lab to identify and target drivers of metastasis in pancreatic cancer.
* Contribute significant input over the direction of the project and bring own ideas.
* Work with orthotopic transplantation models of pancreatic cancer, flow cytometry, spatial transcriptomics and proteomics, single-cell, single-nuclei and bulk RNA‑sequencing, drug and CRISPR strategies in mouse models and organoids of pancreatic cancer, and analysis of human pancreatic tissues.
* Collaborate with the team, communicate effectively, and contribute to other projects beyond your own.
Requirements
* Hold or be about to receive a PhD in a relevant discipline.
* Strong background in molecular biology, cell biology, tissue culture techniques, mouse work and models of cancer.
* Prior knowledge/expertise in pancreatic cancer and/or metastasis biology highly desirable.
* Expertise in data analysis (bulk and single-cell RNA sequencing, spatial transcriptomics) highly desirable.
* Ability to work effectively as part of a diverse and inclusive team, be engaging, collaborative, good communicator and creative thinker, able to find solutions to problems and contribute intellectually and experimentally to other projects beyond your own.
Fixed‑term: The funds for this post are available for 2 years in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online. Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role.
If you have any queries regarding the application process, please contact: mailbox-hr@cruk.cam.ac.uk.
Please quote reference SW49033 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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