Job Overview
Orion Pharma seeks an experienced Global Asset Lead (GAL) to lead a high‑performing Global Program Team (GPT) in a dynamic matrix environment, integrating Clinical, Regulatory, CMC, Medical Affairs, and Commercial functions for a priority oncology program. The role is based in Cambridge, Massachusetts (USA); Cambridge, UK; or Espoo, Finland, and reports directly to the Chief Medical Officer, Oncology Therapy Area.
Key Responsibilities
* Lead the creation and annual update of the Integrated Development Plan (IDP), ensuring clinical, regulatory, technical, and commercial workstreams are harmonized.
* Develop, refine, and execute the Target Product Profile (TPP) to achieve a differentiated label that meets regulatory and pay‑or‑market needs.
* Partner with Medical Affairs and Clinical to drive evidence generation (including RWE and HEOR) supporting market access and reimbursement.
* Act as the central decision‑maker for the GPT, aligning all functions on the asset’s primary objectives.
* Serve as the primary liaison between R&D (CMC/Clinical) and downstream functions to ensure launch‑readiness from supply and value‑proposition perspectives.
* Manage cross‑functional priorities, trade‑offs, and resource constraints to keep the program on track.
* Act as lead presenter for the asset at senior executive governance meetings, securing funding and alignment for major milestones.
* Establish clear “Go/No‑Go” decision points and objectively present data to drive portfolio‑level prioritization.
* Lead risk assessments and develop robust contingency scenarios for clinical failures, regulatory shifts, or competitive market entries.
* Strategize and execute line extensions into new indications, earlier lines of therapy, and novel combination regimens.
* Ensure the IDP includes global geographic considerations (e.g., China/Japan) and mandatory pediatric investigation plans.
* Lead collaborations with academic cooperative groups and manage Joint Steering Committees for co‑development assets.
* Serve as the asset expert for due diligence on potential in‑licensing opportunities and maintain relationships with Key Opinion Leaders.
* Continuously monitor the oncology landscape to adjust strategy in response to emerging “Standard of Care” shifts or competitor data readouts.
What We Offer
We provide a supportive culture that encourages excellence, personal growth, and a clear purpose in improving the lives of patients. Career paths and development opportunities are available to support innovation and professional growth.
Our Expectations
* Mandatory advanced degree: Ph.D. in Life Sciences, Pharm.D., or equivalent (e.g., MD).
* Minimum 15 years of R&D experience in pharma/biotech, including at least 8 years in Oncology Asset Leadership or a comparable matrix role.
* Documented success in leading a program through a global regulatory submission (NDA/BLA/MAA) and subsequent commercial launch.
* Demonstrated ability to influence and lead large cross‑functional teams without direct line‑management authority.
* Experience managing large‑scale program budgets and applying NPV/Asset Valuation models.
* Capability to pivot between high‑level strategic discussions and technical deep‑dives into clinical or CMC data.
* Exceptional executive presence and the ability to challenge senior leaders to achieve the best outcome for the asset.
* Unwavering commitment to clinical data integrity and delivering meaningful outcomes to cancer patients.
How To Apply
Please submit your CV, cover letter, and salary expectations in English by May 10, 2026.
Approved medical examination (including drug testing) and a security clearance are required prior to employment.
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