Overview
About Us: You rarely get the chance to change an entire industry. But that's the position we find ourselves in. Join us, and you’ll help scale cures to patients that need them sooner. We’ve developed fully-automated cell manufacturing sites powered by custom robotics to scale therapies to millions of patients. Last year, patients were cured of diseases like Parkinson’s and vision loss using stem-cell derived cells, but today these Regenerative Medicines are produced by hand, making them expensive and hard to scale. With our automated CDMO, these therapies can now be scaled globally at low cost. We’ve announced partnerships across multiple therapies and raised $24m to expand into the market faster. Within the next 12-18 months, neurons grown on our machines will be going into Parkinson’s patient brains. We’ve assembled a world-class team with ex-Dyson engineers and Nature-published scientists. You can learn more about your potential Mytos teammates here: Team. Mytos is backed by Y Combinator, the most successful startup program in the world which produced companies such as Airbnb, Dropbox, and Ginkgo Bioworks.
Role We are looking for a high-growth stem cell scientist to join our biology team and push the limits of automation in cell therapy manufacture. This is a unique opportunity to learn how to execute projects at the interface of engineering and biology. We believe in autonomy, and you should expect to run your own projects and overcome hurdles with team members available to advise as you require. You will be interfacing with multiple disciplines across biology, hardware and software, so you can expect to learn about these different disciplines as part of the role.
Core Responsibilities
* Characterising how different approaches to automation impact adherent cell lines, human pluripotent stem cells (iPSC or ESC) and differentiated cell types
* Develop and validate automated cell culture protocols for various cell types, with an emphasis on stem cell derived regenerative therapies
* Work collaboratively with hardware and software teams on research and development projects related to automated cell handling
* Provide direct support and technical assistance to customers using Mytos’ automated cell culture platforms
* Contribute to general lab and inventory management tasks
* The role may require occasional weekend work and travel to customer sites (national and international)
Required Skills & Experience
* PhD (or MSc with >2 years industry experience) in cell biology or a related discipline
* Hands-on experience optimising human ESC/iPSC culture and differentiation protocols in a process development capacity
* Experience with core molecular cell biology techniques, such as DNA/RNA isolation, qPCR, immunostaining, image analysis, flow cytometry and ELISA
* Robust experimental design and data analysis capabilities
* Demonstrated ability to plan, manage and execute complex projects with multiple dependencies
* Excellent teamwork and communication skills
Desired Qualities
* Prior experience working in process development (PD) teams or manufacturing science and technology (MSAT) teams for cell therapy production
* Familiarity with regulatory guidelines (MHRA, EMA or FDA) surrounding the development and GMP manufacture of advanced therapy medicinal products (ATMPs)
* Familiarity with technology transfer into GMP
* Experience working with iPSC derived neuronal cell types including dopaminergic neurons and retinal pigmented epithelial cells
* Experience working on the development of hardware systems that interface directly with biology
Benefits
* Competitive salary with stock options
* Collaborative team environment with very high potential to learn new skills
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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