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Upstream bioprocess technical lead

Newbridge (Caerphilly)
SRG
Posted: 9 October
Offer description

Job Title: Upstream Bioprocessing Technical Lead - 6 Month Contractor

Vacancy type: 6 Month contract position - Potential to extend

Salary: Great salary

Location: Crumlin - Wales

Are you a passionate bioprocess expert in Microbial Fermentation scale up seeking a new challenging contract? SRG are exclusively working with a global life science company who are looking for an Upstream Microbial Fermentation SME to support their scale up projects.


The Upstream Bioprocess Technical Lead Role

As the Upstream Bioprocess Technical Lead, you will be responsible for providing technical expertise throughout the early stages of design review, bioprocess optimisation, scale-up, and transfer strategy for Microbial Fermentation projects. You will support the technical inputs that drive successful design reviews and scale-ups, using your in-depth knowledge of bioreactor operations and maintenance, as well as mentoring junior staff.

The Upstream Bioprocess Technical Lead will collaborate with cross-functional teams to ensure the successful delivery of the company's portfolio. This is an exciting opportunity to make a real impact and contribute to the company's growth and innovation.


Key Responsibilities of the Upstream Bioprocess Technical Lead

* Provide subject matter expertise support for projects involving troubleshooting, scale-up, and downstream recovery of recombinant bacteria and yeasts
* Demonstrate a thorough understanding of biological processes, geometric factors, and mathematical models involved in scale-up
* Operate and maintain glass and stainless steel bioreactors at small (1L) and large scales (up to 250L)
* Drive optimization of existing processes to improve efficiency and reduce costs
* Proficiently use bioprocessing software and simulation tools to support operations
* Assist with the identification of technologies and equipment to improve and facilitate transfer and production programmes
* Maintain precise records of batch performance, reports, and analytics


Qualifications and Experience

To be successful in this role, you should have:

* A degree (ideally PhD) in microbiology, molecular biology, biotechnology, or chemical engineering
* Essential: Extensive recent experience in fermentation technologies for proteins, including antigens and enzymes using E.Coli and Yeast.
* Essential: Proven recent expertise in bioprocess optimization, scale-up, and transfer to regular production up to 100L (200L highly desirable)
* Essential: Bioreactor and Media Design for process scale up.
* Excellent understanding of microbiology, biotechnology, and biochemistry
* Proficiency in operating and maintaining glass and stainless steel bioreactors

We are an equal opportunities employer and welcome applications from all qualified candidates.

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