Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges. We have an exciting opportunity for a Senior Bioinformatician to join Tree of Life programme on a 3 year fixed term contrac t at Wellcome Sanger Institute. About the Role: The purpose of this role is to contribute to the study of the diversity and evolution of cell type programs. Specifically, the successful candidate will analyse large-scale single-cell transcriptomics datasets from diverse species; support wet-lab development by performing rapid quality-control assessments and preliminary evaluations of newly generated data; and co-develop, refine, and integrate computational pipelines to advance these efforts. This is an exciting opportunity to contribute to a pioneering effort at the intersection of evolutionary genomics, single-cell biology, and biodiversity research. About You: You will have experience in advanced single-cell data analysis and you will work with genome data from diverse organisms. You will work very closely with a single-cell transcriptomics specialist in our team and with a postdoctoral researcher, and you will also have the opportunity to interact with other groups working on the BCA initiative. Essential Technical Skills: Postgraduate qualification, or equivalent working experience, in Bioinformatics, Software development, Computer Science, or related discipline, Proficiency in single-cell data analysis Experience of UNIX/Linux and shell scripting Proficiency in one or more scripting languages, (e.g. Python or Perl) Demonstratable experience in the fields of genomics, data processing and high-throughput data analysis Experience with running software on a compute farm, cluster, or cloud environment Experience designing and running genomics pipelines in languages such as Nextflow Competencies and Behaviours: Ability to prioritise, manage workload, and deliver agreed activities consistently Ability to work collaboratively with a range of stakeholders at all levels Ability to communicate effectively (verbal and written) with all levels of management & staff High degree of initiative and self-motivation Ability to effectively explain technical issues to non-technical users Ability to actively question and listen to be able to problem solve High level of problem solving/analytical skills Ability to mentor junior members of the team Ability to successfully lead projects About Us: Building on the high-quality genomes generated by the Tree of Life programme, our team is actively implementing single-cell sequencing approaches to systematically generate cell type molecular atlases across organisms. This is part of the broader Biodiversity Cell Atlas initiative (BCA). Other Information: Application Process: Please apply by submitting your CV and a supporting Cover letter. Your cover letter should clearly cover the following three areas: 1. Your background and previous research experience 2. Your relevant skills and how they align with the role 3. Your motivation for applying for this position Salary per annum: £44,905 - £53,000 Role Profile Informatician/ Data Scientist job family: Grade 2 Contract Type: 3 year contract Recruitment Process: Shortlisting w/c 19th January, Interviews w/c 26th January or w/c 2nd March Closing date: 18th January 2026 Hybrid Working at Wellcome Sanger: We recognise that there are many benefits to Hybrid Working; including an improved work-life balance, with more focused time, as well as the ability to organise working time so that collaborative opportunities and team discussions are facilitated on campus. The hybrid working arrangement will vary for different roles and teams. The nature of your role and the type of work you do will determine if a hybrid working arrangement is possible. Equality, Diversity and Inclusion: We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world. We have a supportive culture with the following staff networks, LGBTQ, Parents and Carers, Disability and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness. The networks are also a place for allies to provide support to others. We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work. That's why we're committed to creating a truly inclusive culture at Sanger Institute. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive. Our Benefits: We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme. The importance of good health and adopting a healthier lifestyle and the commitment to reduce work-related stress is strongly acknowledged and recognised at Sanger Institute. Sanger Institute became a signatory of the International Technician Commitment initiative In March 2018. The Technician Commitment aims to empower and ensure visibility, recognition, career development and sustainability for technicians working in higher education and research, across all disciplines.