Contract type: Fixed term for 2 years in the first instance Hours: Full-time About the role We are looking for an experienced Clinical Trial Manager to join the Surgical Intervention Trials Unit (SITU), and lead on a large national multi-centre NIHR-HTA funded trial. funded trial in prostate cancer surgery (PRESIDENT trial). The Trial Manager will coordinate the implementation and running of the PRESIDENT trial across participating hospital sites in the UK. This is a fantastic opportunity to play a pivotal role in the success of this randomised trial from start to finish. The PRESIDENT trial is an world-first innovative trial examining the changes in survival and health-related quality of life in patients with newly diagnosed hormone-sensitive low-volume metastatic prostate cancer after treatment with either standard of care, or standard of care plus radical prostatectomy (RP). Over 800 patients will be recruited in up to 26 NHS Trusts across the UK and the entire trial is expected to last around 8 years. The postholder will act as Trial Manager within the SITU Group, principally responsible for the overall running and management of the PRESIDENT clinical trial. This will involve supporting the participating clinical centres, tracking progress at each centre and taking appropriate action to ensure good recruitment, compliance with the protocol and the quality and timeliness of the data collection. There are some logistical complexities in managing the PRESIDENT trial, working with multiple stakeholders within the University, in other Universities and across the NHS, as well as with Patient and Public Involvement representatives. The Trial Manager will also provide regular feedback on progress of the trial to the Chief Investigator and SITU Senior Team and ensure the study is established and run in accordance with OCTRU Standard Operating Procedures. The Trial Manager will also work across other projects within SITU as a part of a multi-disciplinary research team. About you The successful candidate will be educated to degree level in a biomedical or associated subject and will have proven experience in clinical research. You must demonstrate excellent written and verbal communication skills, with the ability to motivate and negotiate at a senior level. You will be expected to use your own initiative to take operational decisions necessary for the smooth running of the trial day to day. You will be confident and friendly, able to work autonomously and have proven skills of organising and managing the work of a professional team. You will be highly computer literate with expertise in the use of word processing, document layouts, spreadsheets and databases. A current knowledge of clinical trial regulations and governance is essential. The role requires a regular pattern of on-site and hybrid working. This full-time post is available from 1st January 2026 and fixed-term for 2 years in the first instance. Application Process Applications for these vacancies are to be made online and as part of the application process you are required to upload your CV and a covering letter. Please quote reference NDS970 on all correspondence. Only applications received before 12 noon on Thursday 20 November 2025 can be considered. Interviews will be held Tuesday 2 December 2025. Committed to equality and valuing diversity We welcome applications from individuals from all backgrounds, including those under-represented within higher education. No applicant or members of staff shall be unlawfully discriminated against on the basis of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation.