Job DescriptionJob Description
What we are looking for:
The Associate Scientist position is a laboratory-based scientific role in a fast-paced, multidisciplinary team environment. In this role, you will be supporting product formulation development and characterization focused on implantable and injectable pharmaceutical devices for controlled drug delivery utilizing Secant Group’s biomaterial platform.
What you will do:
* Formulate and characterize drug-loaded polymer formulations designed for long-acting implantables, injectables, and oral gastroretention devices to support customer projects and internal investigations
* Execute pre-formulation studies, such as drug particle size analysis, SEM, light microscopy, milling, and sieving
* Characterize drug-polymer miscibility and physiochemical interactions between polymers and various drugs, using DSC, TGA, rheometry
* Analyze formulations using FTIR and Raman spectroscopy to determine drug-polymer mixing efficiency, drug loading, and content uniformity
* Setup and run dissolution studies and analyze dissolution media to determine drug release profiles using HPLC to quantify drug concentration
* Setup and run degradation studies and analyze sample weight, dimensions, and topography to determine polymer degradation behavior
* Perform wet chemistry experiments, like Soxhlet extraction, Karl Fischer titrations, and acid/base titrations
* Collaborate with other teammates within R&D to achieve project goals
Who you are:
* BS in chemistry, biochemistry, chemical engineering, biomedical engineering, pharmaceutics, pharmaceutical sciences, or a related discipline with 0-2 years of experience
* Knowledge of biomaterials specifically biodegradable polymers or polyurethanes
* Exposure to controlled release drug delivery applications
* Desire to develop formulation and characterization skills for drug-polymer dosage forms
* Ability to learn polymer processing techniques, including dispensing, formulation, mixing, milling, extrusion, dispersions, emulsions, molding, casting, and coatings
* Ability to learn test methods and equipment, including mechanical testing (MTS, Instron), DSC, TGA, FTIR, Raman, Dissolution, HPLC, Rheometry, SEM, Light Microscopy, Particle Size Analysis, Titrations, Extractions
What we offer:
* Annual Bonuses
* 401k with excellent company match
* Health Insurance: Medical with Rx plan / Dental / Vision
* Company Paid Short-Term and Long-Term
* Generous Paid Time off and Holiday Pay
Who we are:
The Secant Group is an advanced technology biomaterials company headquartered in Telford, Pennsylvania, with manufacturing facilities in Quakertown and Perkasie, Pennsylvania. Secant provides innovative solutions through next- materials, structures, textile designs, and process technologies for the medical device, pharmaceutical, aerospace and energy markets.
#J-18808-Ljbffr