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Quality manager, atc operational quality

London
Vertex Pharmaceuticals
Quality manager
Posted: 21 September
Offer description

Quality Manager, ATC Operational Quality


Quality Manager, ATC Operational Quality

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Company Name: Vertex Pharmaceuticals
Type of Role: Contract position, Inside IR35
Contract length: 12 months
Location: London, Paddington
Department: Quality Assurance

Looking for opportunities with purpose, impact and possibilities? Our client, Vertex, is a global biotechnology company that invests in scientific innovation. As they grow their pipeline at pace, they are strengthening their reputation for creating transformative medicines for people with serious diseases.

General Summary:
The Apheresis Quality Operations Manager will support the activation of commercial gene therapy Authorized Treatment Centers. The role will perform quality risk assessments and assist with completion of quality agreements, provide operational support for commercial site selection and activation of apheresis and cell-therapy laboratory centers. This role will be supporting the activation of the Authorized Treatment Centers (commercial sites) and will work closely with the Apheresis and Infusion Operations team and the QA Audit team in qualifying sites partnering to provide life saving cell and gene therapy to patients in need.

The Quality Manager will complete the execution of the quality Risk Management Plans that will govern the monitoring and oversight by QA and business functions, working closely with the business stakeholders and the functions within the Quality organization with the objective of ensuring transparency for gaining insights regarding operational risks and mitigations.
This individual is expected to demonstrate success in engaging teams and stakeholders for collaboration in advancing quality outcomes and operational excellence through business and Quality.

The Quality Manager is responsible to support real time treatment center assessment activities within VCGT Quality. The Quality Manager will utilize their technical expertise to optimize interdisciplinary understanding and synergy with the group and integrate activities with other departments to shape a cohesive environment.

Key Duties and Responsibilities:

* Work closely with the Audit and Inspection quality function to establish the audit strategy for Auditing and Performance oversight to evaluate treatment centers ensuring compliance with standards established by applicable regulatory, licensing, and accrediting bodies
* Conduct treatment center Audits where required
* Actively engage with the Audit Management, Vender Management and Apheresis Infusion Operations functions on site qualifications
* Establish and maintain Quality Agreements
* Work with the business areas on site selection
* Provide QA support of change controls, investigations, CAPA’s and effectiveness checks
* Responsible for identifying risks and communicating gaps for process/systems
* Coordinate preparation activities with SMEs
* Real-time Inspection Readiness
* Develop, utilize, and continue to mature tools to ensure efficiency in execution
* Support initiatives associated maintaining relevant inspection related history for inspection readiness purposes
* Identify areas of improvement and participate in process improvement initiatives
* Additional as needed support to processes, systems, procedures to ensure continuous Quality improvement
* Additional activities as needed to support the Quality Systems
* Author/Revise Standard Operating Procedures and associated forms.

Knowledge and Skills:
* Strong apheresis and/or cellular therapy Quality or Operations background
* Project Management Skills
* Operational QA experience with experience with the following is preferred:
* Inspection support roles
* Quality System background
* Understanding of GMP/GDPs/GTP and applicable guidelines/guidance
* Ability to collaborate with cross-functional teams
* Excellent technical writing, presentation, and communication skills
* Experience conducting investigations, performing Root Cause Analysis, and identifying CAPA

Education and Experience:
* Bachelor’s / Masters degree required
* Background in Quality Assurance supporting apheresis, transplant, or cell-therapy lab in a biotech/pharma or healthcare setting


Seniority level

* Seniority level

Not Applicable


Employment type

* Employment type

Contract


Job function

* Job function

Quality Assurance
* Industries

Biotechnology Research and Pharmaceutical Manufacturing

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